The effects may be so critical that experts advise cardiovascular disease patients to remain inside during hurry hour traffic. In the united kingdom, the government will need to submit air quality plans to the European Commission by the finish of 2015. The ruling came after the government failed to comply with European limits on nitrogen dioxide arranged to protect health and outlined in europe Air Quality Directive . The European Commission also had taken Belgium and Bulgaria to court over poor quality of air and Sweden was presented with a final warning. Sound pollution increases the threat of CVD, including hypertension and heart disease. In Europe, it is estimated to contribute to at least 10 000 premature deaths because of cardiovascular disease and stroke every year.That may cause fluid to back up into the lungs, which can make it hard to breathe. ‘There has been a suspicion that there is a circulating hormone or some material that can reverse some of the aging procedure,’ Lee said. The Harvard group honed in on a hormone known as GDF-11, which declines with age in mice. The researchers had taken GDF-11 from young, healthy mice and offered it to aged mice with heart failure. ‘The heart is not known for being a regenerative organ. So I actually secretly suspected that people would not see any impact in these experiments,’ Wagers said.